Qihui Zhou (PI)
Laboratory of Biomaterials for Translational Medicine
Email: qihuizhou@qdu.edu.cn
Phone: 86-17660670299
Group website: https://www.x-mol.com/groups/BMTMers?lang=en
Education
Ph.D, University of Groningen/University Medical Center in Groningen, the Netherlands, 2018. (Academic tree: Interdisciplinary Science)
M.S., Donghua University, China, 2014.
B.S., Qilu University of Technology, China, 2011.
Positions
2021-present: Guest Associate Editor/Topic Editor, Frontiers in Bioengineering and Biotechnology (IF: 5.89) and Frontiers in Chemistry (IF: 5.229)
2020-present: Youth Editorial Board, Military Medical Research (IF: 3.329)
2019-present: Scientific Director, Stomatology Center, the Affiliated Hospital of Qingdao University (QDU).
2018-present: Director, Center for Precision Medicine, QDU
2018-present: Associate Professor, Institute of Translational Medicine, QDU
Research Interest
My work focuses on the development of advanced biomaterials with unique chemical, physical, and biological properties to assist the therapy of challenging diseases, such as antibacterial, hemostasis, tissue repair and regeneration, and cancer. The clinical translation of our biomaterials-based strategies is the ultimate goal of our group.
Professional Memberships
American Chemical Society
Chinese Society of Biomaterials
Shandong Society of Biomedical Engineering
Publications (#equal contribution, *corresponding author)
(Total citation: 1251, H-index: 19, Data from Google scholar)
1. Zheng Wang, Xiaojing Wang, Yingruo Wang, Yanli Zhu, Xinqiang Liu*, Qihui Zhou*. NanoZnO-modified titanium implants for enhanced anti-bacterial activity, osteogenesis and corrosion resistance. Journal of Nanobiotechnology 2021, 19:353. (IF: 10.435)
2. Yiwen Chen #, Huilin Zhu #, Yuanping Hao, Zhanyi Sun, Peili Shen, Qihui Zhou*. Preparation of Fucoidan-based Electrospun Nanofibers and their Interaction with Endothelial Cells. Frontiers in Bioengineering and Biotechnology 2021. Doi: 10.3389/fbioe.2021.739209. (IF: 5.89)
3. Yanli Zhu, Zheng Wang, Longjian Bai, Jing Deng *, Qihui Zhou *. Biomaterial-based Encapsulated Probiotics for Biomedical Applications: Current Status and Future Perspectives. Materials&Design 2021. (Accepted; IF: 7.991)
4. Lubin Liu, Zeyu Han, Fei An, Xuening Gong, Chenguang Zhao, Weiping Zheng, Li Mei, Qihui Zhou *. Aptamer-based biosensors for the diagnosis of sepsis. Journal of Nanobiotechnology 2021, 19 (1): 1-22. (IF: 10.435)
5. Weiping Zheng, Yuanping Hao, Danyang Wang, Hailin Huang, Fangze Guo, Zhanyi Sun, Peili Shen, Kunyan Sui, Changqing Yuan *, Qihui Zhou *. Preparation of triamcinolone acetonide-loaded chitosan/fucoidan hydrogels and its potential application as an oral mucosa patch. Carbohydrate Polymers 2021. DOI: 10.1016/j.carbpol.2021.118493. (IF: 9.381)
6. Xiangyi Yin#, Yuanping Hao#, Yun Lu, Dongjie Zhang, Yaodong Zhao, Li Mei, Kunyan Sui, Qihui Zhou*, Jilin Hu*. Bio-multifunctional Hydrogel Patches for Repairing Full-thickness Abdominal Wall Defect. Advanced Functional Materials 2021: 2105614. (IF: 18.808)
7. Yuanping Hao, Weiping Zheng, Zhanyi Sun, Demeng Zhang, Kunyan Sui, Peili Shen, Peifeng Li*, Qihui Zhou*. Marine polysaccharide-based composite hydrogels containing fucoidan: preparation, physicochemical characterization, and biocompatible evaluation. International Journal of Biological Macromolecules 2021, 183: 1978-1986. (IF: 6.953)
8. Zheng Wang#, Li Mei#, Xinqiang Liu*, Qihui Zhou*. Hierarchically hybrid coatings on Ti implants for enhanced antibacterial activity and osteogenesis. Colloids and Surfaces B: Biointerfaces 2021, 204: 111802. (IF:5.268)
9. Min Li#, Wenshuai Deng#, Jun Zhang, Weiping Zheng, Tao Yu*, Qihui Zhou*. Aligned electrospun PLLA/graphene microfibers with nanotopographical surface modulate the mitochondrial responses of vascular smooth muscle cells. Advanced Materials Interfaces 2021, 2100229. (IF: 6.147)
10. Weiping Zheng, Qihui Zhou*, Changqing Yuan*. Nanoparticles for oral cancer diagnosis and therapy. Bioinorganic Chemistry and Applications 2021, 9977131. (IF: 7.778)
11. Yanjing Ji, Zeyu Han, Han Ding, Xinkai Xu, Danyang Wang, Yanli Zhu, Fei An, Shang Tang, Hui Zhang, Jing Deng*, Qihui Zhou*. Enhanced Eradication of Bacterial/fungi Biofilms by Glucose Oxidase-modified Magnetic Nanoparticles as a Potential Treatment for Persistent Endodontic Infections. ACS Applied Materials & Interfaces 2021, 13: 17289–17299. (IF: 9.229)
12. Yanli Zhu, Lubin Liu, Zhanyi Sun, Yanjing Ji, Danyang Wang, Li Mei, Peili Shen, Zhixin Li, Shang Tang , Hui Zhang, Qihui Zhou*, Jing Deng*. Fucoidan as a marine-origin prebiotic modulates the growth and antibacterial ability of Lactobacillus rhamnosus. International Journal of Biological Macromolecules 2021, 180: 599-607. (IF: 6.953)
13. Liangliang Yang#, Sara Pijuan-Galito#, Hoon Suk Rho#, Aliaksei S Vasilevich#, Aysegul Dede Eren#, Lu Ge#, Pamela Habibović, Morgan Alexander, Jan de Boer, Aurélie Carlier, Patrick van Rijn*, Qihui Zhou*. High-Throughput Methods in the Discovery and Study of Biomaterials and Materiobiology. Chemical Reviews 2021, 121: 4561–4677. (IF: 60.622)
14. Yun He#, Wenwen Zhao#, Zuoxiang Dong, Yanjing Ji, Min Li, Yuanping Hao, Demeng Zhang, Changqing Yuan, Jing Deng, Peng Zhao *, Qihui Zhou *. A biodegradable antibacterial alginate/carboxymethyl chitosan/Kangfuxin sponges for promoting blood coagulation and full-thickness wound healing. International Journal of Biological Macromolecules 2021, 167: 182-192. (IF: 6.953)
15. Qi Zhang, Yanjing Ji, Weiping Zheng, Mingzhe Yan, Danyang Wang, Min Li, Junbo Chen, Xiao Yan, Qiang Zhang, Xiao Yuan *, Qihui Zhou *. Electrospun Nanofibers Containing Strontium for Bone Tissue Engineering. Journal of Nanomaterials. 2020: 1257646. (IF: 2.986)
16. Yuanping Hao #, Wenwen Zhao #, Liyu Zhang, Xi Zeng, Zhanyi Sun, Demeng Zhang, Peili Shen, Zhixin Li, Yantao Han, Peifeng Li*, Qihui Zhou*, Bio-multifunctional Alginate/Chitosan/Fucoidan Sponges with Enhanced Angiogenesis and Hair Follicle Regeneration for Promoting Full-Thickness Wound Healing. Materials & Design 2020, 193: 108863. (IF: 7.991)
17. Baowei Li, Yuzhen Li, Longgang Hu, Ying Liu, Qihui Zhou, Man Wang, Yi An, Peifeng Li, Role of Circular RNAs in the Pathogenesis of Cardiovascular Disease. Journal of Cardiovascular Translational Research 2020, 13: 572–583. (IF: 4.132)
18. Zhongjie Yu, Qi Li, Jing Wang, Yali Yu, Yin Wang, Qihui Zhou*, Peifeng Li*, Reactive Oxygen Species Related Nanoparticle Toxicity in the Biomedical Field. Nanoscale Research Letters 2020, 15: 115. (IF: 4.703)
19. Yan Liu, Wenshuai Deng, Liangliang Yang, Xiuxiu Fu, Zhibin Wang, Patrick van Rijn *, Qihui Zhou *, Tao Yu*, Biointerface topography mediates the interplays between endothelial cells and monocytes. RSC Advances 2020, 10: 13848-13854. (IF: 3.361)
20. Lu Han, Liangliang Yang, Patrick van Rijn, Qingde Yin, Yanyan Yang, Yan Liu, Min Li, Mingzhe Yan, Qihui Zhou*, Tao Yu* and Zhexun Lian*, Biointerface topography regulates phenotypic switching and cell apoptosis in vascular smooth muscle cells, Biochemical and Biophysical Research Communications 2020, 526: 841-847. (IF: 3.575)
21. Qihui Zhou, Jiawen Chen, Yafei Luan, Petteri A. Vainikka, Sebastian Thallmair, Siewert J. Marrink, Ben L. Feringa*, Patrick van Rijn*. Unidirectional rotating molecular motors dynamically interact with adsorbed proteins to direct the fate of mesenchymal stem cells, Science Advances2020, 6: eaay2756. (IF: 14.136, 中科院大类一区)
22. Xiaohui Qiu, Shuo Xu, Yuanping Hao, Brandon Peterson, Baowei Li, Kai Yang, Xiaofang Lv, Qihui Zhou*, Qiuxia Ji*. Biological effects on tooth root surface topographies induced by various mechanical treatments, Colloids and Surfaces B: Biointerfaces 2020, 188: 110748. (IF: 5.268)
23. Guangyue Zu, Yi Cao, Jingjin Dong, Qihui Zhou, Patrick van Rijn, Min Liu*, and Renjun Pei*. Development of an AS1411-Conjugated α-Cyclodextrin-Based Polyrotaxane MRI Contrast Agent for Tumor Targeted Imaging, ACS Applied Bio Materials 2018, 2 (1): 406-416.
24. Qihui Zhou, Lu Ge, Carlos F. Guimarães, Philipp T. Kühn, Liangliang Yang, Patrick van Rijn*. Development of a Novel Orthogonal Double Gradient for High-Throughput Screening of Mesenchymal Stem Cells-Materials Interaction, Advanced Materials Interfaces 2018: 1800504. (IF: 6.147, 中科院大类二区)
25. Qihui Zhou, Zhiyuan Zhao, Gang Zhang, Ryan C. Chiechi*, Patrick van Rijn*. Directing stem cells with gold nanowire arrays, Advanced Materials Interfaces 2018: 1800334. (IF: 6.147, 中科院大类二区)
26. Gwenda F. Vasse, Philipp T. Kühn, Qihui Zhou, Shardul A. Bhusari, Catharina Reker-Smit, Barbro N. Melgert*, Patrick van Rijn*. Collagen morphology influences macrophage shape and marker expression in vitro, Journal of Immunology and Regenerative Medicine, 2018, 1: 13-20.
27. Qihui Zhou, Huilan Zhang, Ya Zhou, Zhepao Yu, Huihua Yuan, Bei Feng, Patrick van Rijn, Yanzhong Zhang*. Alkali-mediated miscibility of GT/PCL for electrospinning homogeneous composite nanofibers for tissue scaffolding. Macromolecular Bioscience, 2017, 17: 1700268. (IF: 4.979)
28. Qihui Zhou, Olga Castañeda Ocampo, Carlos F Guimarães, Philipp T Kühn, Theo G van Kooten, Patrick van Rijn*. Screening platform for cell contact guidance based on inorganic biomaterial micro/nanotopographical gradients. ACS Appiled Materials & Interfaces, 2017, 9 (37): 31433-31445. (IF: 9.229)
29. Qihui Zhou, Patrick Wünnemann, Philipp T. Kühn, Joop de Vries, Marta Helmin, Alexander Böker, Theo G van Kooten, Patrick van Rijn*. Mechanical properties of aligned nanotopologies for directing cellular behavior. Advanced Materials Interfaces 2016, 3, 18: 1600275. (IF: 6.147)
30. Qihui Zhou, Philipp T Kühn, Thirsa Huisman, Elsje Nieboer, Charlotte Van Zwol, Theo G Van Kooten, Patrick Van Rijn*. Directional nanotopographic gradients: a high-throughput screening platform for cell contact guidance, Scientific Reports 2015, 5: 16240. (IF: 4.379)
31. Qihui Zhou#, Jing Xie#, Min Bao, Huihua Yuan, Zhaoyang Ye, Xiangxin Lou, Yanzhong Zhang*. Engineering aligned electrospun PLLA microfibers with nano-porous surface nanotopography for modulating the responses of vascular smooth muscle cells, Journal of Materials Chemistry B 2015, 3 (21): 4439-4450. (IF: 6.331)
32. Qihui Zhou, Min Bao, Huihua Yuan, Shifang Zhao, Wen Dong, Yanzhong Zhang*. Implication of stable jet length in electrospinning for collecting well-aligned ultrafine PLLA fibers, Polymer 2013, 54 (25): 6867-6876. (IF: 4.430)
33. Shifang Zhao#, Qihui Zhou#, Yunze Long, Guanghui Sun, Yanzhong Zhang*. Nanofibrous patterns by direct electrospinning of nanofibers onto topographically structured non-conductive substrates, Nanoscale 2013, 5 (11): 4993-5000. (IF: 7.790)
Book Chapter (#equal contribution, *corresponding author)
1. “Electrospun Nanofibers. Chapter 6: Improving fiber alignment during electrospinning.” Editors: Mehdi Afshari; Authors: Huihua Yuan#, Qihui Zhou#, Yanzhong Zhang*. Elsevier. 2016; Reference: B978-0-08-100907-9.00006-4.1.
2. “Exploring Combined Influences of Material Topography, Stiffness and Chemistry on Cell Behavior at Biointerfaces”. Author: Qihui Zhou. ISBN (printed version): 978-94-034-0780-7.
