Yaqiong Dong, Ph.D, Assistant Prefessor.
Institute of Translational Medicine, The Affiliated Hospital of Qingdao University, College of Medicine, Qingdao University, Qingdao 266021, Shandong, China.
E-mail：joanjoan_2012@sina.cn
Research Areas
Chemical Biology
Education & Positions
Peking University, Ph.D, 2018.
Peking University, Postdoctoral Scholar, 2018-2022.
Qingdao University, Assistant Prefessor, 2023-.
Awards & Honors
Outstanding postdoctoral fellow of Peking University, 2019.
Outstanding postdoctoral fellow of Peking University Health Science Center, 2019.
Research Interests
Studies of pharmacological actions of putative metal ions and bioactive natural products on the occurrence or at symptomatic stages of diseases for discovery of targeted preventive/therapeutic agents, including: (1) Macromolecular "lymphatic-like" drainage pathways and cell signal transduction in metabolic diseases (neurodegenerative diseases, tumors, diabetes, etc.); (2) Antioxidant response mechanism and screening of mitochondrial protective agents; (3) Discovery and development of chemoprophylaxis from food and traditional Chinese medicine for chronic diseases prevention/therapy.
Grants and Fundings
National Natural Science Foundation of China (NSFC 22207008).
Grant from Beijing Association for Science and Technology.
Enterprise authorized items.
Granted Patents
ZL 201611231409.X (Transfer of technological achievements 2020).
ZL 202111194384.1
Selected Publications
1. Yaqiong Dong, Ting Xu, Lan Yuan, et al. (2023) Cerebrospinal fluid efflux through dynamic paracellular pores on venules as a missing piece of the brain drainage system.
2. Bo Feng#, Yaqiong Dong#, Bing Shang, et al. (2022) Convergent Protein Phosphatase Inhibitor Design for PTP1B and TCPTP: Exchangeable Vanadium Coordination Complexes on Graphene Quantum Dots. Advanced Functional Materials 32(5), 2108645.
3. Yaqiong Dong, Tessandra Stewart, Lidan Bai, et al. (2020) Coniferaldehyde attenuates Alzheimer’s pathology via activation of Nrf2 and its targets. Theranostics 10(1), 179.
4. Yaqiong Dong, Tessandra Stewart, Yue Zhang, et al. (2019) Anti-diabetic Vanadyl complexes reduced Alzheimer’s disease pathology independent of amyloid plaque. SCIENCE CHINA Life Sciences 62(01), 128.
5. Jiaojiao Du, Bo Feng, Yaqiong Dong, et al. (2020) Vanadium coordination compounds loaded on Graphene Quantum Dots (GQD) exhibit improved pharmaceutical properties and enhanced anti-diabetic effects. Nanoscale 12, 9219.
6. Chang Tan, Yaqiong Dong, Jing Wang, et al. (2019) Vanadyl acetylacetonate attenuates Aβ pathogenesis in APP/PS1 transgenic mice depending on intervention stage. New Journal of Chemistry 43, 17588.
7. Yaqiong Dong#, Jun Yang#, Hongmei Liu, et al. (2015) Site-Specific Drug-Releasing Polypeptide Nanocarriers Based on Dual-pH Response for Enhanced Therapeutic Efficacy against Drug-Resistant Tumors. Theranostics 5(8), 890.
8. Xue Li，Lidan Bai，Yaqiong Dong, et al. (2016) Vanadyl complexes work with cinnamaldehyde in promoting cell viability under the β-amyloid burden in SH-SY5Y neural cells. Journal of Chinese Pharmaceutical Sciences 10, 754.
9. Yaqiong Dong, Jun Yang, Jinchao Zhang, et al. Nano-Delivery Vehicles/Adjuvants for DNA Vaccination Against HIV. (2016) Journal of Nanoscience & Nanotechnology 16(3), 2126.
10. Chunyan Dai, Gong Cheng, Yaqiong Dong, et al. (2013) Thulium Ion Promotes Apoptosis of Primary Mouse Bone Marrow Stromal Cells. Biological Trace Element Research 156(1-3), 188.
