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卓越人才:王曼

2016年09月27日 15:47  点击:[]

王曼,女,1988年出生,博士,讲师。

2014年毕业于武汉大学,同年进入青岛大学医学部工作,2015年入选青岛大学第三层次卓越人才。主要研究病毒致病机制及其防治策略,成功筛选获得多种病毒候选疫苗,同时阐明了候选疫苗的免疫保护机制,并将相关研究成果发表在国际主流刊物上。

现主持山东省自然科学基金1项,参与国家自然科学基金重点项目和面上项目等6项;发表SCI论文12篇,累计影响因子63.936;其中以第一作者或通讯作者身份在Applied Microbiology and Biotechnology(影响因子3.376)等杂志上发表SCI论文5篇。

研究方向

1.细胞重编程研究

2.抗病毒疫苗筛选及其免疫保护机制研究

3.病毒相关肿瘤发生机制研究

代表论文:(#第一作者,*通讯作者)

1.Man Wang*, Shuai Jiang, Yefu Wang, Recent Advances in the Production of Recombinant Subunit Vaccines inPichia pastoris,Bioengineered, 2016 Apr; 7(3): 155-165.

2.Man Wang*, Shuai Jiang, Zhenwei Han, Bing Zhao, Li'ao Wang, Zhixia Zhou, Yefu Wang*, Expression and Immunogenic Characterization of Recombinant gp350 for Developing a Subunit Vaccine against Epstein-Barr Virus, Applied Microbiology and Biotechnology, 2016, 100(3): 1221-1230.

3.Man Wang, Shuai Jiang, Xiaoying Liu, Yefu Wang*, Expression, Purification, and Immunogenic Characterization of Epstein-Barr Virus Recombinant EBNA1 Protein in Pichia pastoris, Applied Microbiology and Biotechnology, 2013, 97(14): 6251-6262.

4.Man Wang, Shuai Jiang, Yefu Wang*, Recombinant VP1 Protein Expressed in Pichia pastoris Induces Protective Immune Responses against EV71 inMice,Biochemical and Biophysical Research Communications, 2013, 430(1): 387-393.

5.Man Wang#, Bianli Gu#, Jie Huang#, Shuai Jiang, Yijie Chen, Yalin Yin, Yongfu Pan, Guojun Yu, Yamu Li, Barry Hon Cheung Wong, Yi Liang, Hui Sun*, Transcriptome and Proteome Exploration to Provide a Resource for the Study ofAgrocybe aegerita, PLos One, 2013, 8(2): e56686.

6. Kun Wang#*, Bo Long#, Fang Liu#, Jianxun Wang, Cuiyun Liu, Bing Zhao, Luyu Zhou, Teng Sun,Man Wang, Tao Yu, Ying Gong, Jia Liu, Yanhan Dong, Na Li, Peifeng Li*, A Circular RNA Protects the Heart from Pathological Hypertrophy and Heart Failure by Targeting miR-223, European Heart Journal, 2016, Jan 21. Pii: ehv713.

7. Kun Wang, Cuiyun Liu, Luyu Zhou, Jianxun Wang,Man Wang, Bing Zhao, Wenke Zhao, Shijun Xu, Lihua Fan, Xiaojie Zhang, Chang Feng, Chaoqun Wang, Yanfang Zhao, Peifeng Li*, APF lncRNA Regulates Autophagy and Myocardial Infarction by Targeting miR-188-3p, Nature Communications, 2015, 6: 6779.

8. Xiaoying Liu, Jingfeng Tang,Man Wang, Qiang Ma, Yefu Wang*, Visual Detection and Evaluation of Latent and Lytic Gene Expression during Epstein-Barr Virus Infection using One-step Reverse Transcription Loop-mediated Isothermal Amplification, International Journal of Molecular Sciences, 2013, 14(12):23922-23940 (IF=2.339)

9. Shuai Jiang, Yijie Chen,Man Wang, Yalin Yin, Yongfu Pan, Bianli Gu, Guojun Yu, Yamu Li, Barry Hon Cheung Wong, Yi Liang, Hui Sun*, A Novel Lectin fromAgrocybe aegeritaShows High Binding Selectivity for Terminal N-acetylglucosamine, Biochemical Journal, 2012, 443(2): 369-378 (IF=4.654)

10. Guojun Yu,Man Wang, Jie Huang, Yalin Yin, Yijie Chen, Shuai Jiang, Yanxia Jin, Xianqing Lan, Barry Hon Cheung Wong, Yi Liang, Hui Sun*, Deep Insight into theGanoderma lucidumby Comprehensive Analysis of Its Transcriptome, PLos One, 2012, 7(8): e44031 (IF=3.73)

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