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讲师:孙腾

2016年09月27日 15:47  点击:[]

 

孙腾,女,1988年出生,博士,讲师。

2015年01月毕业于中国科学院动物研究所,获得博士学位;2015年02月进入青岛大学转化医学研究院工作,任讲师。曾揭示长链非编码RNA-MDRL调控microRNA-484在细胞核中的加工过程,阐明了MDRL对细胞凋亡和线粒体分裂的抑制作用,明确了MDRL的抗心肌梗死功能(相关成果发表于Plos Genetics. 2014杂志上,共同第一作者)。现主持中国博士后基金面上项目1项,参与国家自然科学基金重点项目2项。

研究方向

1.piRNA调控心肌细胞凋亡和心肌梗死的机制研究

2. MicroRNA与心血管疾病研究

3.心肌细胞死亡机制研究

代表论文:(#第一作者,*通讯作者)

1. Wang K#,Sun T#, Li N#, Wang Y#, Wang JX, Zhou LY, Long B, Liu CY, Liu F and Li PF*. MDRL lncRNA regulates the processing of miR-484 primary transcript by targeting miR-361,Plos genetics,2014, 10(7):e1004467(#These authors contributed equally)

2. 2. Wang K*#, Long B#, Liu F#, Wang JX, Liu CY, Zhao B, Zhou LY,Sun T, Wang M, Yu T, Gong Y, Liu J, Dong YH, Li N, Li PF*. A circular RNA protects the heart from pathological hypertrophy and heart failure by targeting miR-223,European Heart Journal, 2016,pii: ehv713[Epub ahead of print]

3. 3. Wang JX#, Zhang XJ#, Li Q, Wang K, Wang Y, Jiao JQ, Feng C,Sun T, Zhou LY, Gong Y, Zhou ZX, Liu J, Wang JL, Li PF*,MicroRNA-103/107 Regulate Programmed Necrosis and Myocardial Ischemia/Reperfusion Injury Through Targeting FADD,Circulation Research, 2015,117(4):352-63

4. 4. Wang K, Zhou LY, Wang JX, Wang Y,Sun T, Zhao B, Yang YJ, An T, Long B, Li N, Liu CY, Gong Y, Gao JN, Dong YH, Zhang J*, Li PF*,E2F1-dependent miR-421 regulates mitochondrial fragmentation and myocardial infarction by targeting Pink1,Nature Communications,2015,6:7619 (*These authors contributed equally)

5. 5. Wang JX#, Gao J#, Ding SL#,Wang K#, Jiao JQ, Wang Y,Sun T, Zhou LY, Long B, Zhang XJ, Li Q, Liu JP, Feng C, Liu J, Gong Y, Zhou Z, Li PF*. Oxidative Modification of miR-184 Enables It to Target Bcl-xL and Bcl-w,Molecular Cell, 2015, 59(1):50-61(#These authors contributed equally)

6. 6. Wang JX#, Zhang XJ#, Feng C,Sun T,Wang K,Wang Y, Zhou LY, Li PF*, MicroRNA-532-3p regulates mitochondrial fission through targeting apoptosis repressor with caspase recruitment domain in doxorubicin cardiotoxicity,Cell death & disease, 2015, 6:e1677 (#These authors contributed equally)

7. 7. Wang Y,Sun T, Wang K, Wang JX, Li PF*, PiRNAs link epigenetic modifications to reprogramming,Histology and Histopathology,2014, 29(12):1489-1497

8. 8. Wang K#, Liu F#, Zhou LY#, Long B, Yuan SM, Wang Y, Liu CY,Sun T, Zhang XJ, Li PF*, The long noncoding RNA CHRF regulates cardiac hypertrophy by targeting miR-489,Circulation research, 2014, 114(9):1377-88(#These authors contributed equally)

9. 9. Wang K, Liu F, Zhou LY, Ding SL, Long B, Liu CY,Sun T, Fan YY, Sun L, Li PF*, Mir-874 regulates myocardial necrosis by targeting caspase-8,Cell death & disease, 2013, 4:e709

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