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特聘教授:周祺惠

2020年03月13日 14:30  点击:[]


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周祺惠,博士,青岛大学“特聘教授”“生物材料与转化医学”课题组负责人(PI),精准医学中心主任,口腔医学中心科研副主任,硕士生导师。山东省高等学校优秀青年创新团队带头人。

2018年博士毕业于荷兰格罗宁根大学医学中心(在权威的ARWU最新世界大学排名第66位),所学专业是生物医学工程。课题组研究方向围绕材料学、组织工程与再生医学、细胞与分子生物学、临床医学等多学科交叉,以先进生物材料为工具重点开展生物材料界面与(干)细胞相互作用、疾病诊断、药物可控释放系统、止血、组织修复与再生、重症医学等方面的基础和应用研究。建立集材料合成、改性、测试和生物学评价与临床研究为一体的跨学科的综合研究平台和研发队伍。另外,课题组的建设和发展也全面依托于青岛大学附属医院口腔医学中心、山东省数字医学与计算机辅助手术重点实验室、重症医学中心、海藻活性物质国家重点实验室等单位。课题组网站:https://www.x-mol.com/groups/BMTMers

迄今为止,已在生物材料及生物医学相关领域的国际著名期刊发表SCI论文30余篇,分别发表在Science Advances, ACS Applied Materials & Interfaces, Nanoscale, Stem Cell Reports, Biomacromolecules, Biofabrication, Advanced Materials Interfaces, Journal of Tissue Engineering and Regenerative medicine等,论文被引用530次,H-index11。已申请世界和中国专利6项。出版专著1本&1章

目前,作为负责人正在主持的项目有国家自然科学基金山东省自然科学基金山东省高等学校青创科技计划透明质酸国家重点实验室开放课题青岛大学人才启动基金以及多项横向课题等。

另外,系美国化学会、荷兰生物材料与组织工程学会、荷兰细胞外基质学会、中国生物材料学会等会员。担任多个著名国际期刊审稿人。目前与荷兰格罗宁根大学、德国亚琛工业大学等保持密切合作。

 

主要研究方向:

1. 生物材料与(干)细胞相互作用的基础研究

2. 生物材料的设计、制备及其在止血、组织修复与再生中的应用

3. 面向临床的生物医用材料与器械研发

4. 纳米材料的制备及其在抗菌、抗病毒、抗癌和治疗脓毒症中的应用

 

代表性论文(*通讯作者,#共同第一作者):

1. Qihui Zhou, Jiawen Chen, Yafei Luan, Petteri A. Vainikka, Sebastian Thallmair, Siewert J. Marrink, Ben L. Feringa* (2016年诺贝尔化学奖得主), Patrick van Rijn*. Unidirectional rotating molecular motors dynamically interact with adsorbed proteins to direct the fate of mesenchymal stem cells. Science Advances 2020, 6: eaay2756. (IF=12.804)

2. Zhongjie Yu, Qi Li, Jing Wang, Yali Yu, Yin Wang, Qihui Zhou*, Peifeng Li*, Reactive Oxygen Species Related Nanoparticle Toxicity in the Biomedical Field. Nanoscale Research Letters. (IF=3.159)

3. Xiaohui Qiu, Shuo Xu, Yuanping Hao, Brandon Peterson, Baowei Li, Kai Yang, Xiaofang Lv, Qihui Zhou*, Qiuxia Ji*. Biological effects on tooth root surface topographies induced by various mechanical treatments. Colloids and Surfaces B: Biointerfaces 2020, 188: 110748. (IF=3.973)

4. Yan Liu, Wenshuai Deng, Liangliang Yang, Xiuxiu Fu, Zhibin Wang, Patrick van Rijn *, Qihui Zhou *, Tao Yu*, Biointerface topography mediates the interplays between endothelial cells and monocytes. RSC Advances, 2020, 10, 13848-13854 (IF=3.049)

5. Lu Han, Liangliang Yang, Patrick van Rijn, Qingde Yin, Yanyan Yang, Yan Liu, Min Li, Mingzhe Yan, Qihui Zhou*, Tao Yu*, Zhexun Lian*, Biointerface topography regulates phenotypic switching and cell apoptosis in vascular smooth muscle cells, Biochemical and Biophysical Research Communications, 2020, 526, 841-847. (IF=2.705)

6. Liangliang Yang, Torben van der Boon, Patrick van Rijn*, Qihui Zhou*, High-throughput analysis of materiobiology. Chemical Reviews, 2018. (Proposal accepted). (IF=54.301)

7. Qihui Zhou, Lu Ge, Carlos F. Guimarães, Philipp T. Kühn, Liangliang Yang, Patrick van Rijn*, Development of a Novel Orthogonal Double Gradient for High-Throughput Screening of Mesenchymal Stem Cells-Materials Interaction. Advanced Materials Interfaces, 2018, 1800504. (IF=4.713)

8. Qihui Zhou, Zhiyuan Zhao, Gang Zhang, Ryan C. Chiechi*, Patrick van Rijn*, Directing stem cells with gold nanowire arrays. Advanced Materials Interfaces, 2018, 1800334. (IF=4.713)

9. Qihui Zhou, Olga Castañeda Ocampo, Carlos F Guimarães, Philipp T Kühn, Theo G van Kooten, Patrick van Rijn*, Screening platform for cell contact guidance based on inorganic biomaterial micro/nanotopographical gradients. ACS Appiled Materials & Interfaces, 2017, 9 (37), 31433-31445. (IF=8.456)

10. Qihui Zhou, Huilan Zhang, Ya Zhou, Zhepao Yu, Huihua Yuan, Bei Feng, Patrick van Rijn, Yanzhong Zhang*, Alkali-mediated miscibility of GT/PCL for electrospinning homogeneous composite nanofibers for tissue scaffolding. Macromolecular Bioscience, 2017, 17, 1700268. (IF=2.895)

11. Qihui Zhou, Patrick Wünnemann, Philipp T. Kühn, Joop de Vries, Marta Helmin, Alexander Böker, Theo G van Kooten, Patrick van Rijn*, Mechanical properties of aligned nanotopologies for directing cellular behavior. Advanced Materials Interfaces, 2016, 3, 18,1600275. (IF=4.713)

12. Qihui Zhou, Philipp T Kühn, Thirsa Huisman, Elsje Nieboer, Charlotte Van Zwol, Theo G Van Kooten, Patrick Van Rijn*, Directional nanotopographic gradients: a high-throughput screening platform for cell contact guidance. Scientific Reports, 2015, 5, 16240. (IF=4.122)

13. Qihui Zhou, Jing Xie, Min Bao, Huihua Yuan, Zhaoyang Ye, Xiangxin Lou, Yanzhong Zhang*, Engineering aligned electrospun PLLA microfibers with nano-porous surface nanotopography for modulating the responses of vascular smooth muscle cells. Journal of Materials Chemistry B, 2015, 3 (21), 4439-4450. (IF=5.047)

14. Qihui Zhou, Min Bao, Huihua Yuan, Shifang Zhao, Wen Dong, Yanzhong Zhang*, Implication of stable jet length in electrospinning for collecting well-aligned ultrafine PLLA fibers. Polymer, 2013, 54 (25), 6867-6876. (IF=3.771)

15. Shifang Zhao#, Qihui Zhou#, Yunze Long, Guanghui Sun, Yanzhong Zhang*, Nanofibrous patterns by direct electrospinning of nanofibers onto topographically structured non-conductive substrates. Nanoscale, 2013, 5 (11), 4993-5000. (IF=6.97)

 

本课题组热忱欢迎来自生物、医学、化学、材料等领域的本科、硕士研究生和博士后研究人员;同时,欢迎医院、高校科研单位和企业人员与我们开展不同形式的合作交流。

课题组承诺以培养一流人才为己任,将尽最大努力为学生未来发展提供各种机会:(1)科研表现优异且有意出国深造者,课题组将积极推荐至欧美知名课题组;(2)共同创业;(3)推荐至公司就业。我的梦想就是助你扬起风帆,追逐远方的梦想!!

邮箱qihuizhou@qdu.edu.cn/zhouqihui521@163.com;电话:17660670299

 

 



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