张银凤，女，博士，讲师。
2015年毕业于中国科学院生态环境研究中心，获得理学博士学位，同年进入青岛大学转化医学研究院工作。从事专业为心血管疾病的发病机制和分子毒理学研究。主持国家自然科学基金1项，山东省自然科学基金项目1项，中国博士后科学基金面上项目1项，青岛市源头创新计划应用基础研究项目1项以及中科院生态环境研究中心环境化学与毒理学国家重点实验室开放基金1项；参与国家自然科学基金重点项目和面上项目等7项。迄今为止，已在生物医学和毒理学相关领域国际高水平期刊发表SCI论文30余篇，其中以第一作者或通讯作者发表SCI论文12篇，分别发表在Molecular Therapy: Nucleic Acid, International journal of biological sciences，Environmental Science & Technology，Science of the Total Environment等国际著名杂志之上。
研究方向
1. 非编码RNA在血管疾病发生发展中的作用机理及调控机制；
2. 血管内皮细胞功能紊乱的调控机制以及对血管疾病的影响；
3. 环境内分泌干扰物与动脉粥样硬化的关系及机制探讨；
4. 探寻血管疾病早期诊断的分子标志物，研制开发相关的诊断治疗产品，推动血管疾病临床治疗的发展。
代表论文：(#第一作者，*通讯作者)
1. Dong-Dong Jia, Hui Jiang, Yi-Fei Zhang, Yu Zhang, Li-Li Qian, Yin-Feng Zhang*. The regulatory function of piRNA/PIWI complex in cancer and other human diseases: The role of DNA methylation; International journal of biological sciences; 2022; 18(8):3358-3373.
2. Zuo YB#, Zhang YF#*, , Zhang R, Tian JW, Lv XB, Li R, Li SP, Cheng MD, Shan J, Zhao Z, Xin H. Ferroptosis in Cancer Progression: Role of Noncoding RNAs. International journal of biological sciences; 2022;18(5):1829-1843.
3. Wen Z-J, Xin H, Wang Y-C, Liu H-W, Gao Y-Y, Zhang Y-F*. Emerging roles of circRNAs in the pathological process of myocardial infarction, Molecular Therapy: Nucleic Acid, 2021, 26, 828-848.
4. Yu Zhang, Yi-Jing Wei, Yi-Fei Zhang, Hao-Wen Liu, Zhang Y-F*. Emerging functions and clinical applications of exosomal ncRNAs in ovarian cancer, Frontiers in Oncology, 2021, 11. 10.3389/fonc.2021.765458.
5. Zhang, Y., Jia, D.-D., Zhang, Y.-F., Cheng, M.-D., Zhu, W.-X., Li, P.-F., Zhang, Y.-F*. The emerging function and clinical significance of circRNAs in Thyroid Cancer and Autoimmune Thyroid Diseases. International journal of biological sciences, 2021, 17, 1731-1741.
6. Zhang, Y.F., Zhang, Y., Jia, D.D., Yang, H.Y., Cheng, M.D., Zhu, W.X., Xin, H., Li, P.F., Zhang, Y.F*. Insights into the regulatory role of Plexin D1 signalling in cardiovascular development and diseases. Journal of cellular and molecular medicine, 2021, 25, 4183-4194.
7. Zhang, Y.F*, Shan, C., Wang, Y., Qian, L.L., Jia, D.D., Zhang, Y.F., Hao, X.D., Xu, H.M. Cardiovascular toxicity and mechanism of bisphenol A and emerging risk of bisphenol S. Science of the total environment, 2020, 723, 11.
8. Zhang, Yin-Feng; Ren, Xiao-Min; Li, Yuan-Yuan; Yao, Xiao-Fang; Li, Chuan-Hai; Qin, Zhan-Fen*; Guo, Liang-Hong; Bisphenol A alternatives bisphenol S and bisphenol F interfere with thyroid hormone signaling pathway in vitro and in vivo, Environmental Pollution, 2018, 237: 1072-1079.
9. Chan Shan*, Yin-Feng Zhang, Xiaodan Hao, Jinning Gao, Xinzhe Chen and Kun Wang*; Biogenesis, functions and clinical significance of circRNAs in gastric cancer, Molecular Cancer, 2019, 18:136
10. Zhang, Yin-Feng; Xu, Wei; Lou, Qin-Qin; Li, Yuan-Yuan; Zhao, Ya-Xian; Wei, Wu-Ji; Qin, Zhan-Fen*; Wang, Hui-Li*; Li, Jian-Zhong; Tetrabromobisphenol A disrupts vertebrate development via thyroid hormone signaling pathway in a developmental stage-dependent manner, Environmental Science & Technology, 2014, 48(14): 8227-8234.
11. Zhang Yin-Feng*; Xu Hai-Ming; Yu Fei; Wang Man; Li Meng-Yang; Xu Tao; Gao Yan-Yan; Wang Jian-Xun; Li Pei-Feng*; Crosstalk between MicroRNAs and Peroxisome Proliferator-Activated Receptors and Their Emerging Regulatory Roles in Cardiovascular Pathophysiology, PPAR Research, 2018, 2018: 8530371.
12. Zhang, Yin-Feng; Li, Yuan-Yuan; Qin, Zhan-Fen*; Wang, Hui-Li*; Li, Jian-Zhong; A screening assay for thyroid hormone signaling disruption based on thyroid hormone-response gene expression analysis in the frog Pelophylax nigromaculatus, Journal of Environmental Sciences, 2015, 34: 143-154.
13. Zhang, Yin-Feng*, Xu Hai-Ming, Yu Fei, Yang Hong-Yu, Jia Dong-Dong, Li Pei-Feng*. Comparison the sensitivity of amphibian metamorphosis assays with NF 48 stage and NF 51 stage Xenopus laevis tadpoles. Toxicology Mechanisms and Methods, 2019, 29(6): 421-427.
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